Collingwood will be without key forward Brody Mihocek following a hamstring injury he sustained during Friday night's win against Carlton.
Pies coach Craig McRae revealed on SEN that Mihocek tore his hamstring during the third term of the victory but battled courageously for the remainder of the game.
“We have Checkers who's done a hamstring and he'll miss probably two to three weeks,” McRae said on Monday.
“Apparently, he did it in the third quarter and didn't come off.
“We said, ‘Why didn't you come off?'. He goes, ‘Oh, I don't know, I just didn't come off'.
“He's a crazy dude. He knew he'd done it and we found out straight after the game, I had no understanding that he actually had done it (during).
“But obviously it's enough to keep him out for a couple of weeks.
“He's going to be a big loss. We'll have to work our way through that, other guys will get some opportunities.”
Mihocek is another familiar name that will be sidelined, joining Beau McCreery (concussion), Lachie Schultz (suspension) and Tom Mitchell (appendicitis) as confirmed outs for Round 9 while Jordan De Goey (osteitis pubis) is unlikely to come up.
Collingwood accepted Schultz's one-match suspension for his strike on Blues wingman Blake Acres while McCreery copped an errant knee to the head, putting him into concussion protocols and the mandatory 12-day period away from football.
Mitchell's ongoing foot issue that saw him managed against Sydney in Round 1 and subsequently pulled from Friday's game has been compounded by the latest appendicitis hiccup.
The 2018 Brownlow medallist was hospitalised and took to social media to reveal the news, with McRae confirming he'll be absent for at least one more week.
The absence of Mihocek, Schultz and McCreery from the senior side will open up three vacancies from players in the VFL given Mitchell and De Goey are unlikely to return.
Reef McInnes will be the likely replacement for Mihocek while Ash Johnson and Nathan Krueger will come into consideration, despite the latter just returning from injury over the weekend.
Small forward Joe Richards has been a positive in the reserves and has been consistently hitting the scoreboard.
Former Saint and pre-season selection Jack Bytel was best afield in the VFL on Saturday while Finlay Macrae is always around the mark.
The club will confirm its latest injury news on Tuesday.
Collingwood will have up until Friday 5 pm to confirm their starting 23 as they prepare for their clash with West Coast at Marvel Stadium on Sunday.