Steele Sidebottom has been substituted from his 300th AFL game after suffering a suspected MCL injury.
Sidebottom limped from the ground in the first term after laying a tackle on North's Cameron Zurhaar, replaced by Collingwood sub Will Hoskin-Elliott.
Speaking to Channel 7 at quarter time, Collingwood's general manager Graham Wright confirmed that the veteran had suffered a knee injury.
"He's done an MCL," Wright said.
"He'll miss the rest of the game unfortunately, his 300th game so we're disappointed but the players can get the job done without him."
Sidebottom has played ten games for the Pies this season, averaging 22.7 disposals per game. The veteran will now be sidelined for the remainder of his milestone game, with the club to release more information on the extent of his injury in the coming days.