Giants star Toby Greene is expected to miss four weeks with a shoulder injury, reportsย Fox Sports'ย Tom Morris.

The report also states that the Harry Perrman will miss multiple weeks after suffering a hamstring injury.

The club could confirm the news as early as Monday morning in a cruel blow for Leon Cameron's side.

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MELBOURNE, AUSTRALIA - SEPTEMBER 15: Toby Greene of the Giants looks dejected after losing the AFL Semi Final match between the Collingwood Magpies and the Greater Western Sydney Giants at Melbourne Cricket Ground on September 15, 2018 in Melbourne, Australia. (Photo by Quinn Rooney/Getty Images)

Greene had been enjoying arguably a career-best season, especially since taking over the captaincy reigns from injured incumbent Stephen Coniglio - averaging 18.7 disposals and booting 22 goals.

The star forward recently added an extra two seasons to his contract until 2026, effectively making him a Giant for life.

Meanwhile, Perryman has also been one of GWS' best players in 2021, averaging 22.7 disposals from six games.

The Giants coming off a narrow four-point loss to Richmond on the weekend to currently sit ninth on the ladder.