GWS key forward Jesse Hogan will miss Sunday's Opening Round contest against Collingwood after the club revealed he broke his thumb.
The Giants already confirmed that prized recruit Jake Stringer would be absent from this weekend's clash, after suffering a hamstring injury in the VFL last week.
And now the New South Wales club has copped a double blow, with Hogan set to be sidelined for two to three weeks after jamming his thumb in a door.
As for Stringer, the Giants are hopeful he returns in Round 3, when they take on Hawthorn in Launceston.
The Giants also revealed ruckman Kieren Briggs is expected to be fit to face the Magpies after being a late out against the Blues last week. Briggs worked through a lengthy training session on Saturday to keep his name in selection consideration.
GWS are already without Tom Green (calf), Callum Brown (hamstring), Ryan Angwin (ankle) and Josh Fahey (foot) for the start of the season through injury.
Fahey is also needing to serve a four-game suspension, which will likely be covered during his rime in recovery, due to his actions at the club's post-season celebrations.
Joe Fonti, Jake Riccardi, Harvey Thomas and Toby McMullin also need to serve two-game bans to start their 2025 campaigns for their roles in the Giants' controversial post-season celebrations.
GWS' Opening Round clash against Collingwood is scheduled for 3:20 pm (AEDT) on Sunday.
