Fremantle midfielder Stephen Hill won't play in their round one clash with Port Adelaide next week after suffering through quad and calf issues in recent weeks.
Ross Lyon ruled Hill out of contention on Tuesday afternoon after failing to appear in any of the club's pre-season clashes.
"He was just getting some little spasms in there, but that's cleared up," coach Ross Lyon said at the club's season launch.
"Hopefully (he'll play) round two. He was slow with a calf, it was unusual for him, he normally moves through."
Hill's brother, Brad, remains a chance to take the park against Port Adelaide, recovering from a quad injury of his own.
"Brad Hill's coming along a lot quicker as evidenced by what he said on the stage (today), so that's pretty exciting," Lyon said.
"But on the back of our JLT2 a lot of people have picked themselves and put a lot of pressure on match committee."
Meanwhile, Harley Bennell won't turn out for Peel this Saturday after sustaining another setback while recovering from a calf injury.
"He's running and moving, so he's just going to have to build up, which is obviously disappointing but it's the sort of the trend we're in," Lyon said.
"Between Harley, our medical and 'S and C' (strength and conditioning), we've got to find a solution because once we do, we know we've got a very good player.
"It's a tough period, but he's held himself. He needs to continue to button down."
Lyon added that new faces Andrew Brayshaw and Bailey Banfield are "very much in the mix" for round one selection.