Carlton defender Sam Rowe will miss the rest of the season after tearing his ACL against Fremantle on Sunday.
The 29-year-old left the ground following a collision with Fremantle captain Nat Fyfe in the opening quarter, but returned to the ground soon after with his knee strapped.
Rowe then left the field once again after his knee collapsed on him in a marking contest, and was subsequently ruled out of the game.
"Sam is a strong character who has been through considerable adversity before and bounced back," Blues football manager Andrew McKay said.
"Although he is clearly disappointed, we know that Sam will tackle his rehabilitation with the dedication and total professionalism that he has shown throughout his football career."