St Kilda defender Nathan Brown has become the latest AFL player to depart his team's interstate hub to return home.

Brown joins Carlton youngster Liam Stocker and Geelong star Gary Ablett Jr in flying home for family reasons.

The Saints confirmed the news of Brown's departure via the club website.

โ€œNathan leaves the hub with the full support of everyone at St Kilda,โ€ Saints Chief Operating Officer Simon Lethlean said.

โ€œHe is such a respected member of our team and the spiritual leader of the connection, culture and standards that we are building here at the Saints.

โ€œThe players and staff love โ€˜the big fellaโ€™ and we will miss him โ€“ but he has made the right call for him and his family, and we are very proud of him for that.โ€

โ€œAt the end of the day, family comes first and for Nathan that means being at home in Victoria right now.โ€

โ€œAt the right time, if Nathan has played his last game for the Saints then we will recognise his contribution appropriately. But for the time being, we wish he and his family all the best.โ€