Sydney's Will Hayward and Carlton's Mitch McGovern have both been ruled out of the remainder of their sides' clash at Marvel Stadium on Saturday afternoon.
Hayward left the field towards the end of the second quarter, after a collision with Kade Simpson.
The Swans have gone on to confirm Hayward has suffered a broken jaw, with the Swans forward now set for some time on the sidelines.
McGovern was taken from the ground early in the third quarter, and the Blues then confirmed his day was over at three quarter time, with a hamstring issue.