Sydney Swans superstar Lance Franklin has suffered a hamstring injury at training on Wednesday, as first reported by The Age's Sam McClure.
The champion forward will undergo scans tomorrow to determine the severity of the issue.
The 33-year old missed his side's Round 1 win over Adelaide due to a knee issue, but was expected to be available for Round 2.
That now seems highly unlikely, with the Swans set to host Essendon at the SCG in just over two weeks time on Saturday June 14.
The four-time Coleman medallist's body has let him down in recent times, having played just one game since the middle of last season.
Sydney Swans General Manager of Football Charlie Gardiner confirmed Franklin's setback but could not provide any more information about the injury.
“Lance hadn’t been participating in contact training this week as we have been gradually building his training load,” Gardiner told sydneyswans.com.
“He was doing some routine running drills at Lakeside Oval this morning when he experienced pain in his hamstring, which is clearly a concern.
“We won’t know the extent of the injury until we have the results of the scan, but it’s a disappointing setback for Lance as he had been progressing well in his preparation for round 2.”